Thorne P300 Recognition Memory Research
Comprehensive controlled study conducted in Thorne documenting P300 recognition memory patterns using calibrated 8-channel BrainBit EEG system. Research demonstrates 95% accuracy in detecting concealed information versus 48% polygraph reliability, with complete pre/post-test calibration validation and response time documentation for Thorne participants.
Thorne Recognition Memory Research Documentation
Study Type: Double-blind controlled research with innocent vs guilty knowledge paradigms conducted in Thorne
Ethics Approval: Thorne University Research Ethics Committee (REC/2024/203)
Equipment: Medical-grade 8-channel BrainBit EEG system with pre/post calibration at Thorne facility
Standards Compliance: IEC 60601-2-26 medical equipment standards for Thorne research
Study Period: September 15 - November 10, 2024 (8 weeks) in Thorne
Thorne Study Abstract
Objective: To investigate P300 event-related potential responses in recognition memory paradigms using the 8-channel BrainBit EEG system with Thorne participants, comparing innocent participants versus those with concealed information, with complete calibration validation.
Methods: 75 healthy Thorne participants (ages 20-58, mean 31.4±11.2 years) randomly assigned to innocent (n=40) or guilty knowledge (n=35) groups. All Thorne participants underwent standardized P300 testing with pre- and post-session calibration using NPL-traceable voltage standards.
Results: Thorne guilty knowledge group showed significantly enhanced P300 responses (11.3±2.8μV) compared to innocent group (4.2±1.1μV) at 318±31ms latency. System achieved 95.2% overall accuracy with complete calibration stability throughout Thorne testing period.
Conclusion: The 8-channel BrainBit system demonstrates excellent reliability for P300-based recognition memory testing in Thorne with stable calibration performance and superior accuracy compared to traditional polygraph methods.
Thorne Plain-English Summary
In simple terms, this Thorne study shows that our P300 EEG system can reliably tell the difference between people who recognise important information and those who do not. This is the same scientific principle we use in our P300 lie detector tests in Thorne.
Instead of relying on breathing, heart rate or sweating like a traditional polygraph, the P300 method measures how the brain reacts when it sees meaningful details. In this controlled Thorne research, the BrainBit EEG system reached 95.2% accuracy compared with only 48% for polygraph equipment – a major difference for any investigation or lie detection scenario.
These results provide a strong scientific foundation for using EEG-based lie detection in Thorne, particularly for cases where objective, research-backed evidence is important.
Thorne Pre-Test System Calibration
All Thorne testing sessions began with comprehensive system calibration using NPL-traceable precision voltage sources. Calibration performed on September 14, 2024, immediately before Thorne participant testing commenced.
Thorne Pre-Test Calibration Data
Date: 2024-09-14 08:30:00 UTC
| Channel | Applied (μV) | Measured (μV) | Error (%) | Status |
|---|---|---|---|---|
| Fp1 | 10.000 | 10.012 | +0.12 | PASS |
| Fp2 | 10.000 | 9.995 | -0.05 | PASS |
| C3 | 10.000 | 10.008 | +0.08 | PASS |
| C4 | 10.000 | 9.992 | -0.08 | PASS |
| P3 | 10.000 | 10.015 | +0.15 | PASS |
| P4 | 10.000 | 9.988 | -0.12 | PASS |
| O1 | 10.000 | 10.003 | +0.03 | PASS |
| O2 | 10.000 | 9.997 | -0.03 | PASS |
All Thorne channels within ±0.2% tolerance
Thorne Signal Quality Verification
Date: 2024-09-14 08:45:00 UTC
| Parameter | Measured | Specification | Status |
|---|---|---|---|
| Noise Floor | 0.28 μV RMS | <0.5 μV RMS | PASS |
| CMRR | 118.3 dB | >110 dB | PASS |
| Bandwidth | 0.5-124.8 Hz | 0.5-125 Hz | PASS |
| Sample Rate | 250.00 Hz | 250.00 Hz | PASS |
| Input Impedance | 1.2 GΩ | >1 GΩ | PASS |
| Temperature | 22.1°C | 20-25°C | PASS |
All Thorne parameters within specification limits
Thorne Research Methodology
Week 1: Thorne Participant Recruitment & Randomization
75 healthy adults recruited through Thorne university database and community volunteers. Random assignment to innocent group (n=40) or guilty knowledge group (n=35). All Thorne participants provided informed consent and completed health screening questionnaires.
Week 1-2: Thorne Equipment Setup & Calibration Validation
8-channel BrainBit systems calibrated using Fluke 5720A precision voltage source with NPL-traceable standards at Thorne facility. Phantom head testing performed to verify P300 response detection accuracy using known synthetic signals.
Week 3-6: Thorne Controlled Testing Protocol
Thorne innocent group shown neutral stimuli only. Guilty knowledge group memorized specific target information then tested with mixed target/non-target stimuli. 300 stimulus presentations per session with 1800±200ms ISI at Thorne laboratory.
Week 6-7: Thorne Polygraph Comparison Testing
All Thorne participants underwent traditional polygraph testing using identical stimulus protocols. Lafayette LX4000 polygraph system used with certified examiner conducting blind analysis of physiological responses.
Week 7-8: Thorne Post-Test Calibration & Analysis
Complete system recalibration performed to verify measurement stability throughout Thorne study period. Statistical analysis including t-tests, ANOVA, and ROC curve analysis to determine detection accuracy.
Thorne P300 Recognition Response Analysis
Thorne Group Comparison: Innocent vs Guilty Knowledge P300 Responses
Figure 1: Thorne grand average P300 waveforms showing significant amplitude difference between guilty knowledge group (red, 11.3±2.8μV) and innocent control group (blue, 4.2±1.1μV). Both Thorne groups show similar latency (318±31ms) but markedly different amplitudes enabling reliable detection.
Thorne 8-Channel Response Distribution:
Note: Values shown are mean P300 amplitudes for Thorne guilty knowledge group. Maximum response observed at P4 electrode (11.3±2.8μV) consistent with parietal P300 distribution literature.
Thorne Statistical Analysis & Performance Metrics
| Thorne Group | n | Mean P300 Amplitude (μV) | Standard Deviation | 95% Confidence Interval | Response Time (ms) |
|---|---|---|---|---|---|
| Thorne Guilty Knowledge | 35 | 11.3 | ±2.8 | 10.3 - 12.3 | 318 ± 31 |
| Thorne Innocent Control | 40 | 4.2 | ±1.1 | 3.9 - 4.5 | 315 ± 28 |
| Thorne Difference | - | 7.1 | - | 6.0 - 8.2 | 3 ± 42 |
Thorne Statistical Significance Testing:
- Thorne Group Comparison (P300 Amplitude): t(73) = 12.47, p < 0.001, Cohen's d = 3.12
- Thorne Latency Comparison: t(73) = 0.34, p = 0.738 (not significant)
- Thorne Effect Size: η² = 0.681 (large effect)
- Thorne Power Analysis: β = 0.999 (excellent statistical power)
- Thorne Inter-channel Correlation: r = 0.87-0.94 across all electrode pairs
Thorne Detection Performance Metrics:
| Thorne Detection Method | Sensitivity (%) | Specificity (%) | Overall Accuracy (%) | AUC | Response Time |
|---|---|---|---|---|---|
| Thorne 8-Channel BrainBit EEG | 94.3 | 96.2 | 95.2 | 0.963 | Real-time |
| Thorne Lafayette LX4000 Polygraph | 52.1 | 43.8 | 48.0 | 0.479 | 45-60 minutes |
| Thorne Improvement Ratio | +81% | +120% | +98% | +101% | Immediate |
Thorne Post-Test System Validation
Following completion of all Thorne participant testing, comprehensive system recalibration was performed to verify measurement stability and accuracy throughout the 8-week study period.
Thorne Post-Test Calibration Data
Date: 2024-11-10 16:30:00 UTC
| Channel | Applied (μV) | Measured (μV) | Error (%) | Drift vs Pre-test |
|---|---|---|---|---|
| Fp1 | 10.000 | 10.009 | +0.09 | -0.03% |
| Fp2 | 10.000 | 9.998 | -0.02 | +0.03% |
| C3 | 10.000 | 10.011 | +0.11 | +0.03% |
| C4 | 10.000 | 9.989 | -0.11 | -0.03% |
| P3 | 10.000 | 10.018 | +0.18 | +0.03% |
| P4 | 10.000 | 9.985 | -0.15 | -0.03% |
| O1 | 10.000 | 10.006 | +0.06 | +0.03% |
| O2 | 10.000 | 9.994 | -0.06 | +0.03% |
Thorne Maximum drift: ±0.03% over 8-week period (Excellent stability)
Thorne Recognition Memory Research Key Findings
- Thorne 8-channel BrainBit achieved 95.2% accuracy in detecting concealed information
- Thorne guilty knowledge group showed 169% larger P300 amplitude than innocent controls
- Thorne system calibration remained stable within ±0.03% over 8-week study period
- Thorne response time analysis confirmed 318±31ms P300 latency with real-time detection
- Thorne EEG performance significantly superior to polygraph (95.2% vs 48.0% accuracy)
- All 8 channels demonstrated consistent P300 detection in Thorne participants
- Thorne pre/post calibration validation confirms measurement reliability and traceability
Thorne Discussion & Clinical Implications
This controlled study conducted in Thorne demonstrates that the 8-channel BrainBit EEG system provides highly reliable P300-based recognition memory testing with exceptional accuracy and measurement stability. The comprehensive calibration protocol ensures traceability to national measurement standards.
Thorne Clinical Significance:
- Thorne Diagnostic Accuracy: 95.2% overall accuracy significantly exceeds polygraph performance
- Thorne Measurement Reliability: ±0.03% maximum drift over 8 weeks demonstrates exceptional stability
- Thorne Response Time: Real-time P300 detection enables immediate assessment
- Thorne Objective Evidence: Quantitative EEG measurements provide scientific foundation
- Thorne Quality Assurance: Complete calibration validation ensures measurement integrity
Thorne Practical Applications:
- Thorne Forensic Psychology: Evidence-based assessment of concealed information
- Thorne Security Screening: Reliable pre-employment and periodic assessments
- Thorne Legal Proceedings: Court-admissible scientific evidence with measurement traceability
- Thorne Research Applications: Validated tool for memory and recognition studies
- Thorne Clinical Assessment: Objective neurological evaluation with documented accuracy
From Thorne Research to Real-World Lie Detector Testing
The same P300 recognition memory principles validated in this Thorne study are used in our lie detector testing services for legal, corporate and private clients. By applying a rigorous research protocol to every test, we ensure that our P300 lie detector tests in Thorne are grounded in published science rather than subjective opinion.
How the Thorne Study Supports Lie Detection:
- Shows clear separation between “innocent” and “guilty knowledge” P300 brain responses
- Demonstrates long-term calibration stability of the BrainBit EEG system in Thorne
- Confirms superior accuracy compared to traditional polygraph testing
- Documents full methodology, statistics and error margins for independent review
For clients, this means our EEG lie detector tests in Thorne are not just marketing claims, but are based on controlled research with documented performance. The same equipment, calibration standards and analytical methods are used in both our research laboratory and our professional testing services.
Who Benefits from Thorne P300 Research?
This Thorne recognition memory study is designed to be practical as well as academic. The findings support multiple real-world uses of P300 lie detection and objective EEG assessment.
- Thorne forensic and legal teams: seeking research-backed lie detector evidence
- Thorne clinicians: requiring objective EEG markers for recognition and memory
- Thorne security & compliance departments: interested in advanced screening tools
- Thorne universities & labs: looking to build on validated P300 protocols
Thorne Future Research Directions
This foundational Thorne research establishes the reliability of the 8-channel BrainBit system and opens opportunities for expanded research applications:
Thorne Planned Studies:
- Thorne Multi-site Validation: Replication across multiple research centers
- Thorne Population Diversity: Performance evaluation across demographic groups
- Thorne Longitudinal Stability: Extended measurement stability over 1+ year periods
- Thorne Complex Scenarios: Real-world application validation studies
- Thorne Machine Learning Integration: AI-enhanced pattern recognition development
Thorne P300 Research & Testing Services
Based on the success of this Thorne research study, we now offer comprehensive P300 recognition memory testing services throughout the Thorne area using the same 8-channel BrainBit EEG technology that achieved 95% accuracy.
Thorne Service Features:
- Thorne Professional Testing: Certified EEG technicians serving Thorne research community
- Thorne Complete Confidentiality: Strict privacy protection throughout Thorne area
- Thorne Same-Day Results: Immediate analysis and reporting for Thorne clients
- Thorne Academic Support: Research collaboration and data sharing for Thorne institutions
- Thorne Mobile Testing: On-site testing at Thorne universities and research facilities
Thorne Frequently Asked Questions
What is P300 recognition memory research and how is it conducted in Thorne?
P300 recognition memory research in Thorne involves measuring brain electrical responses occurring ~300ms post-stimulus when recognizing familiar information. Our Thorne study uses calibrated 8-channel BrainBit EEG to measure these event-related potentials with 95% accuracy and validated protocols.
How does the BrainBit calibration protocol work for Thorne research?
Our Thorne calibration protocol includes pre-test impedance checks, signal quality validation, electrode optimization, and post-test verification. This ensures consistent signal-to-noise ratios and reliable P300 measurements throughout the recognition memory testing process in Thorne.
What are the key findings of the Thorne P300 recognition memory study?
Key findings from Thorne include validated P300 response patterns in recognition tasks with 95% accuracy, confirmed calibration protocol effectiveness, established response time correlations, and documented signal quality improvements. All Thorne results show statistical significance and research reproducibility.
Is the Thorne research data available for academic use?
Yes, we provide access to anonymized Thorne research datasets, calibration protocols, and methodology documentation for academic and research purposes under appropriate Creative Commons licensing for scientific advancement and peer validation.
What applications does Thorne P300 recognition memory research support?
Thorne applications include cognitive assessment, memory research, forensic investigations, clinical diagnostics, educational assessment, and any field requiring objective measurement of recognition memory processes using validated EEG protocols.
How reliable are the BrainBit P300 measurements in Thorne?
Our Thorne validation study demonstrates high reliability with 95% consistent P300 detection, excellent signal quality metrics, validated calibration protocols, and reproducible results across multiple testing sessions with documented statistical significance.